2017年10月

CRISP_SCIENCE@ScienceCrispImpeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9Mol Cell 1019 https://t.co/T9xszRTkl2… https://t.co/b9JFZ3K5ja2017/10/23 08:56:32 CRISP_SCIENCE@ScienceCrispReconstitution of UCP1 using #CRISPR/Cas9 i ... もっと読む

[出典] Pontes-Quero S, ~ Benedito R4. “Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis” Cell. 2017 Aug 10;170(4):800-814.e18.Elsner M. “Mosaic mice ace functional genomics” Nat Biotechnol. N&V. 20 ... もっと読む

The CRISPR Journal@CRISPRjournalWe’re launching The CRISPR Journal! Get more details at Booth #300 #ashg17 https://t.co/h6StbRlWFm2017/10/20 00:35:53 CRISP_SCIENCE@ScienceCrisp#CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent ... もっと読む

[出典] Stella S, Alcón P, Montoya G. “Class 2 CRISPR–Cas RNA-guided endonucleases: Swiss Army knives of genome editing” Nat Struct Mol Biol. 2017 Oct 16.バクテリアの獲得免疫応答機構として進化してきたCRISPR-Casシステムの中で、クラス2タイプⅡ CRISPR-Ca ... もっと読む

[出典] “CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy” Ma L [..] Bolon DN. Proc Natl Acad Sci U S A. Published online before print October 16, 2017. [背景] 特定の疾病に薬剤耐性をもたらす変 ... もっと読む

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