2018年04月

出典[論文] "Cracking the DNA Code for V(D)J Recombination" Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. Mol Cell. 2018 Apr 19;70(2):358-370.e4. Published online 2018 Apr 5.[構造] PDB-6CIL Pre-Reaction Complex (PRC) (intact/int ... もっと読む

出典[論文] "Systematic analysis of complex genetic interactions" Kuzmin E [...] Andrews BJ, Boone C, Myers CL. Science. 2018 Apr 20;360(6386), eaao1729.[展望] "If two deletions don't stop growth, try three" Walhout AJM. Science. 2018 Apr 20;360(6386): 269 ... もっと読む

1.[レビュー]CRISPR/Cas9技術の癌研究と癌療法への応用"CRISPR/Cas9 for cancer research and therapy" Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M (DKFZ). Semin Cancer Biol. 2018 Apr 16.多用途なCRISPR/Cas9;sgRNAsの設計とソフトウエア;プール型ライブラ ... もっと読む

"CRISPR-Directed In Vitro Gene Editing of Plasmid DNA Catalyzed by Cpf1 (Cas12a) Nuclease and a Mammalian Cell-Free Extract" Sansbury Brett M, Wagner Amanda M, Nitzan Erez, Tarcic Gabi, Kmiec Eric B. The CRISPR Journal 2018 Apr 1.Acidaminococcus sp. Cpf1 ... もっと読む

出典"Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases" Hudson AM, Stephenson NL, Li C, Trotter E, Fletcher AJ, Katona G, Bieniasz-Krzywiec P, Howell M, Wirth C, Furney S, Miller CJ, Brognard J. Sci Signal 17 Apr 2018;11(52 ... もっと読む

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