2018年10月

[出典]News & Views "Designing efficient translation" Gorochowski TE,  Ellis T. Nat Bioetchnol. 2018 Oct 11.;論文 "Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli" Cambray G, Guimaraes JC, A ... もっと読む

1. Staphylococcus epidermidis由来タイプⅢ-A CRISPR Cas10-Csmのサブ複合体構造およびcrRNA結合状態の構造を、X線結晶解析とクライオ電顕法 (5.2 Å分解能)で決定[出典] "Structural Organization of a Type III-A CRISPR Effector Subcomplex Determined by X-ray Crystal ... もっと読む

1. CRISPR-Casによりヒト癌モデルにもなり得るTP53変異ブタを作出[出典] "Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation" Tanihara F, Hirata M, Nguyen NT, Le QA, Hirano T, Tak ... もっと読む

[出典] "Minimal PAM specificity of a highly similar SpCas9 ortholog" Chatterjee P, Jakimo N, Jacobson JM. Sci Adv. 2018 Oct 24. (bioRxiv 2018-02-02*)要約MITの研究チームは2018年2月2日にbioRxivに5'-NNGT-3' PAMを認識するStreptococcus canis由来Cas9 (ScCas9) ... もっと読む

1. [Correspondence] Anti-CRISPR (Acr)タンパク質登録・共有データサイト公開[出典] "A Unified Resource for Tracking Anti-CRISPR Names" Bondy-Denomy J, Davidson AR, Doudna JA, Fineran PC, Maxwell KL, Moineau S, Peng X, Sontheimer EC, Wiedenheft B. The CRISPR ... もっと読む

↑このページのトップヘ