2018年11月

[出典] "Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9" Bubeck F, Hoffmann MD [..]  Eils  R, Niopek D. Nat Methods. 2018 Oct 30.要約微生物由来のAcrタンパク質がCRISPR-Casエフェクター阻害活性を酵母*やヒト細胞でも**示すことから、Ac ... もっと読む

[出典] "Efficient CRISPR/Cas9-based genome editing and its application to conditional genetic analysis in Marchantia polymorpha" Sugano SS [..] Kohchi T. PLoS One. 2018 Oct 31.概要「陸上植物の祖先の特徴をもつ苔類ゼニゴケ (Marchantia polymorpha)の全ゲノム ... もっと読む

1. AAV-CRISPR/Cas9による体細胞GUCY2D遺伝子編集を介してマウスとマカクの網膜の構造・機能を改変[出典] "Somatic gene editing of GUCY2D by AAV-CRISPR/Cas9 alters retinal structure and function in mouse and macaque" McCullough KT [..] Boye S. Hum Gene Ther. 201 ... もっと読む

[出典]"rec-YnH enables simultaneous many-by-many detection of direct protein–protein and protein–RNA interactions" Yang JS, Garriga-Canut M, Link N, Carolis C, Broadbent K, Beltran-Sastre V, Serrano L, Maurer SP. Nat Commun. 2018 Sep 14.背景タンパク質と ... もっと読む

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