2019年03月

1. [レビュー] 部位特異的ヌクレアーゼによるゲノム編集実用ガイド[出典] REVIEW "A Practical Guide to Genome Editing Using Targeted Nuclease Technologies" Porter SN, Levine RM, Pruett-Miller SM (St. Jude Children's Research Hospital). Compr Physiol. 2019-03-1 ... もっと読む

[出典] "Sherlock Biosciences Licenses Wyss Technology to Create Affordable Molecular Diagnostics" Brownell L. Wyss Institute News 2019-03-21;"Sherlock Biosciences Launches to Provide Better, Faster and More Affordable Diagnostic Testing Worldwide Throug ... もっと読む

[出典] "Enhanced Cas12a editing in mammalian cells and zebrafish" Liu P [..] Lawson ND, Wolfe SA. Nucleic Acids . 2019-03-20. University of Massachusetts Medical Schoolの研究グループは今回、Cas9と異なるPAMを認識し、crRNAにより (tracrRNA不要)ガイドされDNa ... もっと読む

[出典] "Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia" Okada H, Nakanishi C  [..] Yamagishi M, Kawashiri M. Sci Rep. 2019-03-18概要 ... もっと読む

[出典] "Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements" Hwang B, Lee W, Yum SY, Jeon Y, Cho N, Jang G, Bang D. Nat Commun. 2019-03-15 (bioRxiv. 2018-07-12)  CRISPR-Casゲノム編集技術の出現によって細胞系譜再構成法 ... もっと読む

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