2019年07月

1. [特許公開] 新奇PAMを認識するStreptococcus canisゲノム編集プラットフォーム[出典] US20190218532A1"Streptococcus canis Cas9 as a Genome Engineering Platform with Novel PAM Specificity"公開日 2019-07-18. 発明者 Jacobson JM, Jakimo NM, Chatterjee P. 権利者 ... もっと読む

[出典] "Targeting Toxic Nuclear RNA Foci with CRISPR-Cas13 to Treat Myotonic Dystrophy" Poosala P, Lindley SR, Anderson KM, Anderson DM. bioRxiv 2019-07-26. University of Rochester School of Medicine and DentistryのAndersonチームは2019年1月に、Prevotella ... もっと読む

[出典] "Biological Plasticity Rescues Target Activity in CRISPR Knockouts" Smits AH, Ziebell F [..] Steinmetz LM, Drewes G, Huber W. bioRxiv 2019-07-26 > Nat Methods. 2019-10-28. (abstract比較結果文末に) EMBL, GlaxoSmithKlineならびにHorizon Genomics Gm ... もっと読む

[出典] "Human Artificial Chromosomes that Bypass Centromeric DNA"  Logsdon GA [..]  Black BE. Cell 2019-07-25.; NEWS RELEASE "Penn Biochemists Streamline Construction Method for Human Artificial Chromosomes" Penn Medicine News 2019-07-25.背景ヒト細胞に ... もっと読む

[出典] "Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions" Ghosh RP, Shi Q [..] Liphardt JT. Nat Commun 2019-07-19. bioRxiv 2018-10-26.Stanford Universityを中心とする米国研究グループは今回、C ... もっと読む

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