2019年10月

1. ヒト前立腺癌における変異型TP53遺伝子のCRISPR/Cas9 HDRを介した修復の効果[出典] Evaluation of the CRISPR/Cas9 directed mutant TP53 gene repairıng effect in human prostate cancer cell line PC-3. Batır MB, Şahin E, Çam FS. Mol Biol Rep.2019-09-30.   ... もっと読む

[出典] CRISPR-PCD and CRISPR-PCRep: Two novel technologies for simultaneous multiple segmental chromosomal deletion/replacement in Saccharomyces cerevisiae. Easmin F [..] Harashima S. J Biosci Bioeng. 2019-10-01.PCR-mediated chromosome splitting (PCS) にC ... もっと読む

[出典] Exploring the Trans‐Cleavage Activity of CRISPR Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor. Dai Y [..] Caplan AI, Liu CC. Angew Chem Int Ed. 2019-09-30.予備実験に基づいてLbCas12aを選択し、電極チップ上のssDNAの密度と ... もっと読む

[出典] Photolabile Semiconducting Polymer Nanotransducer for Near‐infrared Regulation of CRISPR/Cas9 Gene Editing. Lyu Y, He S [..] Pu K. Angew Chem Int Ed. 2019-09-30.近赤外光で一重項酸素を生成するポリマー骨格に、一重項酸素で切断されるリンカー (チオケタ ... もっと読む

[出典] Time origin and structural analysis of the induced CRISPR/Cas9 megabase-sized deletions and duplications involving the Cntn6 gene in mice. Pristyazhnyuk IE, Minina J [..] Serov OL. Sci Rep. 2019-10-02.著者らは先行研究で、コンタクチン6をコードするC ... もっと読む

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