2019年12月

[出典] Plasmid-based and -free methods using CRISPR/Cas9 system for replacement of targeted genes in Colletotrichum sansevieriae. Nakamura M, Okamura Y, Iwai H. Sci Rep. 2019-12-12.  鹿児島大学の研究グループは今回、組換え頻度が低い植物病原菌類C. sanse ... もっと読む

[出典] Ex/in vivo gene editing in hepatocytes using “all-in-one” CRISPR-AAV vectors with a self-linearizing repair template. Krooss S, Dai Z [..] Ott M. iScience. 2019-12-12.  Hannover Medical Schoolを主とする研究グループは今回、サイズ5.73 kbのSL ... もっと読む

[出典] Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system. Matson AW, Hosny N, Swanson ZA, Hering BJ, Burlak C. PLoS One. 2019-12-10.  University of Minnesota School of Medi ... もっと読む

[出典] Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Sun Y [..] Liu F, Zhu Z, Meng A. Genome Res. 2019-12-12.  Zebrafish All Genes Knockout Consortium (ZAKOC)からの初の成果報告1,029遺伝子に変異を誘導し、生殖細胞系列に ... もっと読む

[出典] A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus. Valderrama JA, Kulkarni SS, Nizet V, Bier E. Nat Commun. 2019-12-16.  微生物に由来するCRISPR-Casシステムにより、微生物のゲノムそしてま ... もっと読む

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