62th Annual Meeting Biophysical Society 
San Francisco California February 17-21,2018
  1. Biophysical Analysis of Cas9 - DNA Interactions and Enzymatic Activity with Electro-Switchable DNA Layers. Felix J. Kroener, Ulrich Rant. https://doi.org/10.1016/j.bpj.2017.11.1394
  2. A PAM-Induced Signalling Activates the Communication between HNH and RUVC in CRISPR-Cas9. Giulia Palermo, Clarisse Ricci, Yinglong Miao, Martin Jinek, J. Andrew McCammon. https://doi.org/10.1016/j.bpj.2017.11.1391
  3. Correlated Single Molecule Twist and Fluorescence Measurements on CRISPR/Cas Systems. Pierre Aldag, Julene Madariaga Marcos, Inga Songailiene, Felix Kemmerich, Virginijus Siksnys, Ralf Seidel. https://doi.org/10.1016/j.bpj.2017.11.1392
  4. Simultaneous Real-Time Observation of DNA Unwinding and Nuclease Domain Activation in Cas9-RNA-DNA Complex via Three-Color Single Molecule FRET. Yanbo Wang, Digvijay Singh, John Mallon, Boyang Hua, Scott Bailey, Taekjip Ha. https://doi.org/10.1016/j.bpj.2017.11.3127
  5. Duplex DNA Destabilization by Type V CRISPR-Cas Nucleases during Interrogation of DNA. Vladimir Mekler, Leonid Minakhin, Konstantin Kuznedelov, Karthik Murugan, Dipali Sashital, Konstantin Severinov. https://doi.org/10.1016/j.bpj.2017.11.1390
  6. Spatial Organization and Dynamics of RNA Processing in Caulobacter Crescentus. Camille Bayas, Jiarui Wang, Marissa K. Lee, Jared M. Schrader, Lucy Shapiro, W.E. Moerner. https://doi.org/10.1016/j.bpj.2017.11.1397
  7. Biophysical Analysis of Cas9-DNA Interactions and Enzymatic Activity with Electro-Switchable DNA Layers. Felix J. Kroener, Ulrich Rant. https://doi.org/10.1016/j.bpj.2017.11.1394
  8. Inhibitory Effect of the DNA Tension on the CRISPR/Cas9 Activities. Suleyman Ucuncuoglu, Kassidy Lundy, Ozgur Sahin. https://doi.org/10.1016/j.bpj.2017.11.1406
  9. Inducible Gene Expression and Protein Localization using CRISPR/DCAS9 and Antiviral Protease Inhibitors. Elliot P. Tague, John Ngo https://doi.org/10.1016/j.bpj.2017.11.1252
  10. Investigating the Mechanism of DNA Recognition by a CRISPR-Cas12a Nuclease. Wei Jiang. https://doi.org/10.1016/j.bpj.2017.11.1389
  11. Solvent Accessibility of CRISPR-CAS9 Target DNA is Correlated with Substrate Specificity. Travis H. Hand, Anuska Das, Emily Duboy, Mitchell Roth, Chardasia Smith, Uriel Baptist, Hong Li. https://doi.org/10.1016/j.bpj.2017.11.1401
  12. Enhancing Mitochondrial Biogenesis with a CRISPR/ndCas9 Adenoviral Vector System in Cardiomyocytes. Deepthi Ashok, Agnes Sidor, Brian O'Rourke.  https://doi.org/10.1016/j.bpj.2017.11.3574
  13. Investigating and Modelling the Target Recognition Dynamics of the CRISPR-Cas Surveillance Complex Cascade. Marius Rutkauskas, Tomas Sinkūnas, Inga Songailiene, Virginijus Siksnys, Ralf Seidel https://doi.org/10.1016/j.bpj.2017.11.1083
  14. CRISPR/Cas9 Created CPVT1 Associated RyR2 Mutations Reliably Reproduces the Calcium Signaling Aberrancy in Human iPSC-CMS. Xiaohua Zhang, Hua Wei, Naohiro Yamaguchi, Martin Morad. https://doi.org/10.1016/j.bpj.2017.11.676
  15. Genome-Scale Biophysical Profiling of CRISPR Interference. Ilya Finkekstein. https://doi.org/10.1016/j.bpj.2017.11.046
  16. Generation and Characterization of CPVT1 Cardiomyocytes using Human Induced Pluripotent Stem Cells and CRISPR/Cas9 Gene Editing. Naohiro Yamaguchi, Xiao-Hua Zhang, Hua Wei, Martin Morad. https://doi.org/10.1016/j.bpj.2017.11.667
  17. CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling. Tangprasertchai NS, Di Felice R, Zhang X, Slaymaker IM, Vazquez Reyes C, Jiang W, Rohs R, Qin PZ. http://www.cell.com/biophysj/pdf/S0006-3495(17)32313-5.pdf / CRISPR Cas9 Mediated DNA Unwinding Detected using Site-Directed Spin Labeling. Tangprasertchai NS, Di Felice R, Zhang X, Slaymaker IM, Vazquez Reyes C, Jiang W, Rohs R, Qin PZ. ACS Chem Biol. 2017 Jun 16;12(6):1489-1493. Published online 2017 May 3. https://doi.org/10.1021/acschembio.6b01137
  18. Enhanced Proofreading Governs CRISPR-Cas9 Targeting Accuracy. Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA. http://www.cell.com/biophysj/pdf/S0006-3495(17)32314-7.pdf / Enhanced Proofreading Governs CRISPR-Cas9 Targeting Accuracy. Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA. Nature. 2017 Oct 19;550(7676):407-410. doi: 10.1038/nature24268. Published online 2017 Sep 20. https://doi.org/10.1038/nature24268
  19. Structure, Function, and Dynamics of Xanthomonas albilineans Cas2 in Type I-C CRISPR-Cas System. Euiyoung Bae, Nayoung Suh. http://www.cell.com/biophysj/pdf/S0006-3495(17)33485-9.pdf / Solution structure and dynamics of Xanthomonas albilineans Cas2 providemechanistic insight on nuclease activity. Jeong M, Kim I, Kim G, Ka D, Kim NK, Bae E, Ryu KS, Suh JY. FEBS Lett. 2018 Jan;592(1):147-155. Published online 2018 Jan 3. https://doi.org/10.1002/1873-3468.12942