[注] hLMR (human lncRNA metabolic regulators); 非アルコール性脂肪性肝疾患 (non-alcoholic fatty liver disease: NAFLD)[出典] "Integrative regulation of hLMR1 by dietary and genetic factors in nonalcoholic fatty liver disease and hyperlipidemia" Jaso-Vera ME ...
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カテゴリ: CRISPR
[レビュー] 標的遺伝子挿入:血友病治療法から切り開かれたCRISPR医薬の最先端
[出典] REVIEW "Targeted Gene Insertion: The Cutting Edge of CRISPR Drug Development with Hemophilia as a Highlight" Zang Z [..] Feng B. BioDrugs 2024-03-15. https://doi.org/10.1007/s40259-024-00654-5 [所属] Chinese U Hong Kong, Hong Kong Institute of Scie ...
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背側線条体におけるTlr3ノックダウンが雄マウスのエタノール消費と急性機能耐性を低下させる
[出典] "Knockdown of Tlr3 in dorsal striatum reduces ethanol consumption and acute functional tolerance in male mice" Dilly GA [..] Messing RO. Brain Behav Immun. 2024-03-16. https://doi.org/10.1016/j.bbi.2024.03.021 [所属] U Texas at Austin, U Pittsburgh ...
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AI抗体設計への第一歩 - VHH抗体のデノボ設計
- 難易度の高い創薬標的への取り組みを前進させるAIが登場、しかし、臨床へはまだ紆余曲折が[出典] NEWS "‘A landmark moment’: scientists use AI to design antibodies from scratch" Callaway E (Senior Reporter). Nature 2024-03-19. https://doi.org/10.1038/d41586- ...
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DNAデータストレージにおけるCRISPR搭載定量キーワード検索エンジン
[出典] "CRISPR-powered quantitative keyword search engine in DNA data storage" Zhang J, Hou C, Liu C. Nat Commun. 2024-03-15. https://doi.org/10.1038/s41467-024-46767-x [所属] U Connecticut Health Center, U Connecticut. 全てがデジタル化される時代になり ...
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