[注] レンチウイルス由来ナノ粒子 (lentivirus-derived nanoparticles: LVNPs)[出典] "Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modificatio ...
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タグ:デリバリー
膠芽腫の放射線治療増感を目的とした細胞外小胞送達型CRISPR/Cas9の開発
[出典] "Engineered Extracellular Vesicle-Delivered CRISPR/Cas9 for Radiotherapy Sensitization of Glioblastoma" Liu X, Cao Z, Wang W [..] Lin W, Li M, Gu J. ACS Nano. 2023-08-30. https://doi.org/10.1021/acsnano.2c12857 [著者所属] Fourth Military Medical U, ...
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DNAナノフレームワークを利用してCRISPR-Cas9システムの癌細胞特異的送達を実現
[出典] "Cascade dynamic assembly/disassembly of DNA nanoframework enabling the controlled delivery of CRISPR-Cas9 system" Song N, Chu Y [..] Yao C, Yang D. Sci Adv. 2023-08-30. https://doi.org/10.1126/sciadv.adi3602 [著者所属] Tianjin U, Tianjin Medical U ...
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CRISPR-Cas9 RNAをLNPで送達することで、高効率で安全なT細胞とHSPC細胞の生体外遺伝子編集を実現
[注] LNP (脂質ナノ粒子);HSPC (ヒト造血幹・前駆細胞)[出典] "Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells" Vavassori V, Ferrari S [..] Naldini L. Blood 2023-08-31. https://doi.org/10.1182/blood.20220193 ...
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標的化mRNA医薬デリバリーに最適なナノ粒子 (NPs) のハイスループット・スクリーニング
[出典] SPOTLIGHT "A high-throughput approach of screening nanoparticles for targeted delivery of mRNA" Khirallah J, Xu Q. Cell Rep Methods. 2023-08-22. https://doi.org/10.1016/j.crmeth.2023.100572 [著者所属] Tufts U."Peptide-encoding mRNA barcodes for the ...
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