タグ:プロテオミクス

[出典] "Noncoding regions are the main source of targetable tumor-specific antigens" Laumont CM, Vincent K [..] Thibault P, Perreault C. Sci Transl Med. 2018-12-05概要癌抗原 (腫瘍特異的抗原; Tumor-specific antigens, TSAs)は癌免疫療法の格好の標的であるが、 ... もっと読む

[出典] "Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments" Benhalevy D, Anastasakis DG, Hafner M. Nat Methods. 2018-11-26.RNAの細胞内小器官局在を解析する手法として、APEX-RIP (RNA immunoprecipitation)やRaPIDな ... もっと読む

[出典] "ProteoStorm: An Ultrafast Metaproteomics Database Search Framework" Beyter D, Lin MS, Yu Y, Pieper R, Bafna V. Cell Syst. 2018 Oct 24. Online 2018-09-26.概要微生物群集の機能的ランドスケープの解明には、メタゲノミクスとメタトランスプリクトミクスに続 ... もっと読む

出典Preview "Human Diseases from Gain-of-Function Mutations in Disordered Protein Regions" Li XH, Babu MM. Cell. 2018 Sep 20. Article "Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs" Meyer K, Kirchner M, Uyar B [..] Diecke ... もっと読む

[出典]"Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates" Alber AB, Paquet ER, Biserni M, Naef F, Suter DM. Mol Cell 2018 Aug 23.[概要]正常な生細胞ではタンパク質の合成と分解と ... もっと読む

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