タグ:免疫・療法

出典[論文] Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Crowther MD [..] Sewell AK. Nat Immunol. 2020-01-20. [NEWS & VIEWS] MR1-RESTRICTED T CELLS - ‘Bohemian Rha ... もっと読む

[出典] MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1. Yan J [..] Teng MWL. Cancer Discovery. 2019-12-11. [関連crisp_bio記事] 2020-01-23 ヒトMHCクラスⅠb 分子のMR1は、癌免疫療法の新たな標的 (2/2) - 汎ヒト・汎がん療法の可能性も ... もっと読む

[論文] An intra-tumoral niche maintains and differentiates stem-like CD8 T cells. Jansen CS, Prokhnevska N [..] Kissick H. Nature 2019-12-11. [NEWS AND VIEWS] Identifying the source of tumour-infiltrating T cells. Kumar Vodnala S, Restifo NP. Nature 2019 ... もっと読む

[出典]NEWS & VIEWS: Antitumour T cells stand the test of time. Reina-Campos M, Goldrath AW. Nature. 2019 Dec;576(7787):392-393[論文] Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Wei J, Long L [..] Chi H. Nature. 2019-12-11. ... もっと読む

[出典] [NEWS & VIEWS] Three is a charm for an antibody to fight cancer/Trispecific antibodies offer a third way forward for anticancer immunotherapy. Garfall AL, June CH. Nature. 2019-11-21.; [論文] Trispecific antibodies enhance the therapeutic efficacy ... もっと読む

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