[出典] "The structure of AcrIC9 revealing the putative inhibitory mechanism of AcrIC9 against the type IC CRISPR–Cas system" Kang YJ [..] Park HH. IUCrJ. 2023 Sept 10(5): pp 624-634. https://doi.org/10.1107/S2052252523007236 [著者所属] Chung-Ang U, Daegu ...
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タグ:構造解析
好熱菌Thermoclostridium caenicola由来の熱安定なCRISPR-Cas13a (TccCas13a) のリボヌクレアーゼ活性の構造基盤
[出典] "Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola " Wang F, Zhang C, Xu H, Zeng W, Ma L, Li Z. J Mol Biol 2023-07-11. https://doi.org/10.1016/j.jmb.2023.168197 [著者所属] Hubei U. R ...
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タイプV-M CRISPR-CasエフェクターCas12m2の応答機構と進化過程
[出典] "Mechanistic and evolutionary insights into a type V-M CRISPR–Cas effector enzyme" Omura SN [..] van der Oost J, Nureki O. Nat Struct Mol Biol 2023-07-17 https://doi.org/10.1038/s41594-023-01042-3 [著者所属] 東大, キュライオ (Currie, Inc) https:// ...
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タイプIV-A CRISPR-Csf複合体:構成, dsDNAターゲッティング, およびCasDinGの動員
[注] CasDinG:タイプIV-A CRISPR-Csf複合体のユニットcsf4[出典] "Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment" Cui N, Zhang J-T [..] Huang H, Jia N. Mol Cell 2023-06-20. https://doi.org/10.1016/j.molcel.2023.05.036 [著者 ...
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1億件規模の高精度予測構造がデータベースの高速・高感度な検索を実現するFoldseek
[出典] "Fast and accurate protein structure search with Foldseek" van Kempen M, Kim SS, Tumescheit C, Mirdita M, Lee J, Gilchrist CLM, Söding J, Steinegger M. Nat Biotechnol 2023-05-08. https://doi.org/10.1038/s41587-023-01773-0 [著者所属] Max Planck In ...
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