タグ:癌

[リンクのみ] "The Application of CRISPR/Cas9 System in Cervical Precancerous Lesions"  Gao C, Wu P, Yu L [..] Huang X, Wang H (華中科技大学).  Research Square 2020-06-25. (Preprint) ... もっと読む

[出典] "Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR" Dhoonmoon A [..] Moldovan GL. Nucleic Acids Res 2020-06-15.  DNA損傷応答は、ゲノムの安定に保ち、 ... もっと読む

[出典] "Chlorin e6 and CRISPR-Cas9 dual-loading system with deep penetration for a synergistic tumoral photodynamic-immunotherapy" Yang C [..] Qian Z. Biomaterials 2020-06-14.  光線力学的療法 (photodynamic therapy; PDT)は 原発腫瘍 (特に表皮癌)治療に有望 ... もっと読む

[出典] "Discovering and validating cancer genetic dependencies: approaches and pitfalls" Lin A, Sheltzer JM. Nat Rev Genet 2020-06-19.  Stanford UのAnn LinとCSHLのJason M. Sheltzerは今回、癌細胞に特異的な必須遺伝子 (以下、癌細胞必須遺伝子)は癌治療の恰好 ... もっと読む

[出典] "Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing" Stangl C [..] van Haaften G, Monroe GR. Nat Commun 2020-06-05.  University Medical Center Utrecht and Utrecht Universityを主とする ... もっと読む

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