タグ:細胞系譜

[出典] "Single-cell lineage tracing by integrating CRISPR-Cas9 mutations with transcriptomic data" Zafar H, Lin C, Bar-Joseph Z. (bioRxiv 2019-05-07) Nat Commun 2020-06-16. [crisp_bio注] 本記事はbioRxiv版に準拠した「CRISPRメモ_2019/05/17-1 [第5項] LinTIM ... もっと読む

 1. Fast-HDRシステム: CRISPR技術によるノックイン細胞株作出を迅速にする多用途ベクターシステムを開発[出典] A Versatile Vector System for the Fast Generation of Knock-in Cell Lines with CRISPR. Perez-Leal O, Nixon-Abell J, Barrero CA, Gordon J, Rico MC. bio ... もっと読む

2020-05-16 Cell論文出版2019-10-23 初稿[出典] An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cell. Bowling S, Sritharan D [..] Hormoz S, Camargo FD. bioRxiv. 2019-10-17 > Cell 2020 ... もっと読む

[出典] "Ordered insertional mutagenesis at a single genomic site enables lineage tracing andanalog recording in mammalian cells" Loveless TB, Grotts JH [..] Liu CC. bioRixv 2019-05-16.背景 CRISPR-CasがDNAに誘導する変異によって細胞事象をDNAに記録し (DNAレ ... もっと読む

1. SpCas9活性の深層学習モデルDeepCas9 (2019-09-20, -11-10, -11-26 追記)[出典] "SpCas9 activity prediction by DeepCas9, a deep learning-based model with unparalleled generalization performance" Kim HK, Kim Y [..] Kim HH. bioRxiv 2019-05-15. > "SpCas9 activ ... もっと読む

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