タグ:薬剤耐性

1. ADAM17とPD1のCRISPR/Cas9ノックアウトによりNK細胞免疫療法の可能性を広げた[出典] "A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy" Pomeroy EJ [..] Moriarity BS. bioRxiv. 2018.Sep 29.NK (ナチュラルキラー)細胞は ... もっと読む

[出典] "Conversion of staphylococcal pathogenicity islands to CRISPR-carrying antibacterial agents that cure infections in mice" Ram G, Ross HF, Novick RP, Rodriguez-Pagan I, Jiang D. Nat Biotechnol. 2018 Sep 24.背景黄色ブドウ球菌 (Staphylococcus aureus) ... もっと読む

[出典] "Prevalence and patterns of higher-order drug interactions in Escherichia coli イタ" Tekin E [..] Savage VM, Yeh PJ. NPJ Syst Biol Appl. 2018 Sep 3. (bioRxiv 2017 Dec 14)概要UCLA、UCおよびSanta Fe Instituteの研究チームは、抗生物質2種類、3種類、4 ... もっと読む

[出典] "Optimized arylomycins are a new class of Gram-negative antibiotics." Smith PA, Koehler MFT [..] Heise CE. Nature. 2018 Sep 12. ;筆頭著者と責任著者とのインタビュー記事"New class of antibiotics discovered" Rikken M. ResearchGate. 2018 Sep 12.背景抗 ... もっと読む

[出典]"Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance" le Sage C, Lawo S, Panicker P, Scales TME, Rahman SA, Little AS, McCarthy NJ, Moore JD, Cross BCS. Sci Rep. 2017 Dec 18;7(1):17693.プール型CR ... もっと読む

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