タグ:CAR-T

出典[論文] "Designed protein logic to target cells with precise combinations of surface antigens" Lajoie MJ, Boyken SE, Salter AI [..] Baker D. Science. 2020-09-25. [Research Highlight] When de novo-designed protein logics meet CAR-T therapies. Xe M, Lu ... もっと読む

2020-09-26 タイトルを改訂, Splitの項のテキストを整理、参考資料を追加, 挿入図を改訂, 原論文の図じへのURLを修正2018-04-30 初稿出典"Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses" Cho JH, Collins JJ, Wong WW. Cel ... もっと読む

[出典] Self-cutting and integrating CRISPR plasmids (SCIPs) enable targeted genomic integration of genetic payloads for rapid cell engineering. Bloemberg [..] McComb S. bioRxiv 2020-09-01.  Human Health Therapeutics Research Center (Ottawa)の研究グルー ... もっと読む

[出典] COMMENTARY "CRISPR-Edited Immune Effectors: The End of the Beginning" Mo F, Heslop HE, Mamonkin M (Baylor College of Medicine). Mol Ther. 2020-03-22.  PD-1 (PDCD1)とTCR α/β (TRAC/TRBC遺伝子)の3遺伝子をノックアウトし、NY-ESO-1/LAGE-1特異的TCRを ... もっと読む

1. [レビュー] デュシェンヌ型筋ジストロフィー (DMD)のCRISPR遺伝子治療[出典] REVIEW "CRISPR Correction of Duchenne Muscular Dystrophy" Min YL, Bassel-Duby R, Olson EN (U. Texas Southwestern Medical Center). Annu Rev Med. 2018-10-31.(2019年1月に最終版出版予 ... もっと読む

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