blogging about crisp bio-S&T, especially CRISPR.


[出典] “Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption” Gopalappa  R, Suresh B, Ramakrishna S,  Kim  H. Nucleic Acids Res. 2018 Mar 23. [背景] CRISPR/Cas9ゲノム編集にはオフターゲット作用が伴うが ... もっと読む

CRISP_SCIENCE@ScienceCrispNature Index 2018 Japan;... some of Japan’s smallest institutions are among the most effic… 06:54:02第5期科学技術基本計画において「超スマート社会 (super smart soci ... もっと読む

CRISP_SCIENCE@ScienceCrisp[INTRODUCTION TO SPECIAL ISSUE]The Cancer Immunotherapy Revolution. Kelly PN. Science 2018 Mar 23;359(6382):1344-13… 06:55:081. [ニュース]過ぎたるは及ばざるがごとし?[出典] pp. 1346-1347 "Too m ... もっと読む

CRISP_SCIENCE@ScienceCrispAssessing security implications of genome editing: Emerging points from an international workshop.Fears R, Ter Meu… 06:36:20CRISP_SCIENCE@ScienceCrispA global observatory for gene editing- Sheil ... もっと読む

出典"Toward an integrated map of genetic interactions in cancer cells" Rauscher B, Heigwer F, Henkel L, Hielscher T, Voloshanenko O, Boutros M. Mol Syst Biol. 2018 Feb 21;14(2):e7656.MINGLE多様なCRISPR/Cas9スクリーン由来のデータを統合しヒト細胞における遺 ... もっと読む