blogging about crisp bio-S&T, especially CRISPR.


[出典] "Retraction of DNA-bound type IV competence pili initiates DNA uptake during natural transformation in Vibrio cholerae" Ellison CK, Dalia TN, Vidal Ceballos A, Wang JC, Biais N, Brun YV, Dalia AB. Nat Microbiol. 2018 Jul;3(7):773-780. Online 2018-0 ... もっと読む

1. 送達法:pH-応答性多機能アミノ脂質*とCRISPR/Cas9ナノ粒子を作成・評価[出典] "Synthesis and Evaluation of pH-Sensitive Multifunctional Lipids for Efficient Delivery of CRISPR/Cas9 in Gene Editing" Sun D [..] Lu ZR. Bioconjugate Chem. 2018-12-24. (*) (1-am ... もっと読む

出典[ニュース] "Better mouse model built to enable precision-medicine research for Alzheimer’s - NIH-funded team shows that introducing genetic diversity improves translatability" NIH News 2018-12-27.[論文] Neuner SM, Heuer SE, Huentelman MJ, O’Connell ... もっと読む

[出典] "CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise" Pertea M [..]  Salzberg SL. Genome Biol. 2018 Nov 28;19(1):208. ; "Thousands of large-scale RNA sequencing e ... もっと読む

[[出典] "The battle over new nerve cells in adult brains intensifies - New methods are needed to settle the debate" Sanders L. ScienceNews 2018-12-201世代前、成人脳では神経細胞は新生しないとされていたが、この社会通念は20年前に覆されたところ、2018年になっ ... もっと読む