blogging about crisp bio-S&T, especially CRISPR.


[出典] Engineering CRISPR Interference System to Repress Class 1 Integron in Escherichia coli". Lia Q [..] Shi L, Tian P. Antimicrob Agents Chemother. 2019-12-23. 華南理工大学、北京化工大学ならびに曁南大学の研究グループが、大腸菌をモデルとして表題の手法 ... もっと読む

[出典] Method of Treating Diseases Associated with Elevated KRAS expression using CRISPR-GNDM system公開日:2019-12-12 US20190376088A1; 2018-08-16 WO2018147343A1 発明者:Yamagata T, Qin Y, Morita H, Akbulut T, Thompson IR. 権利者:EdiGENE (エディジーン ... もっと読む

[出典] High-frequency random DNA insertions upon co-delivery of CRISPR-Cas9 ribonucleoprotein and selectable marker plasmid in rice. Banakar R [..] Wang K. Sci Rep. 2019-12-27.   CRISPR-Cas9をRNPの形で送達するとCas9-sgRNAのゲノムへの組み込みを回避しオ ... もっと読む

[出典] Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila. Liu Q, Zhang Y [..] Tian C. Biotechnol Biofuels. 2019-12-23.天津工业生物技术研究所の研究グループが、Acida ... もっと読む

[出典] Specificity Assessment of CRISPR Genome Editing of Oncogenic EGFR Point Mutation with Single-Base Differences. Bae T, Kim H  [..] Lee SH, Ham BJ, Hur JK. Molecules. 2019-12-22.  肺癌において活性化しているEGFRには19種類のエクソン欠損と21種類のミ ... もっと読む