blogging about crisp bio-S&T, especially CRISPR.


[出典] "CRISPR/Cas9-targeted mutagenesis of the tomato susceptibility gene PMR4 for resistance against powdery mildew" Santillán Martínez MI [..] Bai Y. BMC Plant Biol 2020-06-19.  Wageningen University & Researchの研究グループは今回、トマトのPMR4遺 ... もっと読む

[出典] "Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells" Chen Y, Liu J [..] Liang P, Songyang Z. Nat Commun 2020-06-19.  クラス2 CRISPR-CasはCRISPR-Casシステムの~10%を占めるに過ぎないが、タイプ IIのCas9, タ ... もっと読む

[出典] "Light-responsive charge-reversal nanovector for high-efficiency in vivo CRISPR/Cas9 gene editing with controllable location and time" Wu Y [..] Zhang T, Xing D. Nano Res 2020-06-18. 華南師範大学の研究グループは今回、980 nmの近赤外光 (NIR)照射によ ... もっと読む

[出典] "A rapid method for detection of mutations induced by CRISPR/Cas9-based genome editing in common wheat" Kamiya Y [..] Kawaura K. Plant Biotechnology 37, 247–251 (2020)  木原生物学研究所と農研機構の研究グループは今回、パンコムギの未成熟胚に、gRN ... もっと読む

[出典] "Generation of knockout rabbits with X-linked severe combined immunodeficiency (X-SCID) using CRISPR/Cas9" Hashikawa Y, Hayashi R [..] Mashimo T, Nishida K. Sci Rep 2020-06-19.  免疫不全動物はヒト細胞または動物細胞を利用したin vivo移植実験に重要 ... もっと読む