blogging about crisp bio-S&T, especially CRISPR.


[出典] REVIEW: CRISPR/Cas systems to overcome challenges in developing the next generation of T cells for cancer therapy. Huang D [..] Peppas NA. Adv Drug Deliv Rev 2020-07-21.  UT Austinの研究グループが、次世代CAR-T療法を目指して、CRISPR/Cas多重遺伝子 ... もっと読む

[出典] Engineering of monosized lipid-coated mesoporous silica nanoparticles for CRISPR delivery. Noureddine A, Maestas-Olguin A [..] Brinker CJ, Serda RE. Acta Biomater 2020-07-20.  U New Mexicoの研究グループから新たなデリバリー法脂質で被覆した (lipid ... もっと読む

[出典] Bidirectional titration of yeast gene expression using a pooled CRISPR guide RNA approach. Bowman EK [..] Alper HS. PNAS 2020-07-20.  酵母代謝モデルiTO077の969遺伝子のプロモーター領域を埋め尽くす (tiling)sgRNAsのライブラリーにCRISPRi (dCas9-Mxi1) ... もっと読む

[出典] Tropism-facilitated delivery of CRISPR/Cas9 system with chimeric antigen receptor-extracellular vesicles against B-cell malignancies. Xu Q, Zhang Z [..] Wang J, Zhou J. J Control Release 2020-07-22. CRISPR/Cas9ゲノム編集の臨床応用には、デリバリー ... もっと読む

[リンクのみ] REVIEW "Computational Methods for Analysis of Large-Scale CRISPR Screens" Lin X [..] Qi LS (Stanford U). Annu Rev Biomed Data Sci. July 2020. ... もっと読む