crisp_bio

blogging about crisp bio-S&T, especially CRISPR.

2020年08月

[出典] In vivo CRISPR screening for phenotypic targets of the mir-35-42 family in C. elegans. Yang B, Schwartz M, McJunkin K. Genes Dev 2020-08-20https://dx.doi.org/10.1101/gad.339333.120 NIDDK/NIHとU. Utahの研究チームは今回、多重化CRISPR-Cas9により、特 ... もっと読む

[出典] Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing. Sgodda M [..] Cantz T. Cells 2020-08-20. https://dx.doi.org/10.3390/cells9091929 Hannover Medical Schoolを主とす ... もっと読む

[出典] Csx3 is a cyclic oligonucleotide phosphodiesterase associated with type-III CRISPR-Cas that degrades the second messenger cA4. Brown S [..] Lawrence M. JBC 2020-08-21. https://dx.doi.org/10.1074/jbc.RA120.014099. [構造情報] PDB-6VJG https://pdbj.o ... もっと読む

[出典] Conditional Recruitment to a DNA-Bound CRISPR–Cas Complex Using a Colocalization-Dependent Protein Switch. Kirkpatrick RL [..] Baker D, Zalatan JG. ACS Synth Biol 2020-08-20. UW Seattleの研究グループは今回、ケージ化したCRISPRa [1]に、DNA結合によ ... もっと読む

[出典] Modeling pediatric AML FLT3 mutations using CRISPR/Cas12a- mediated gene editing. Rivera-Torres N, Banas K, Kmiec EB. Leuk Lymphoma. 2020-08-20. https://dx.doi.org/10.1080/10428194.2020.1805740 Helen F Graham Cancer Center & Research Instituteの研 ... もっと読む

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