crisp_bio

blogging about crisp bio-S&T, especially CRISPR.

2020年10月

[出典] "Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq" Liu X, Kimmey JM, Matarazzo L [..] Veening JW. Cell Host Microbe 2020-10-28. 肺炎レンサ球菌 (Streptococcus pneumoniae )の病原性S. pneumoniaeは往々にし ... もっと読む

[出典] "SNP CRISPR: A Web Tool for SNP-Specific Genome Editing" Chen C, Rodiger J, Chung V, Viswanatha R, Mohr SE, Hu Y, Perrimon N. G3 (Bethesda) 2020-02-06.  Harvard Medical Schoolの研究グループは、CRISPR/Cas9ゲノム編集において、参照(標準)ゲノムをベー ... もっと読む

[出典] "CRISpy-pop: a web tool for designing CRISPR/Cas9-driven genetic modifications in diverse populations" Stoneman HR [..] Hittinger CT. bioRxiv 2020-06-20. [Preprint][注] CRISpy-popは"a Python-based web application for the design of CRISPR/Cas9 sgRNA ... もっと読む

[出典] Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Ochiai H [..] Nikaido I. Sci Adv 2020-06-17; 理研・広島大学ニュースリリース 2020-06-15「哺乳類細胞における突発的遺伝子発現動態を網羅的に決定!!~iPS細胞の精 ... もっと読む

[出典] "Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens" Marquart KF, Allam A, Janjuha S [..] Krauthamme M, Schwank G. bioRxiv 2020-07-05.   U Zurichの研究グループは、CB ... もっと読む

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