blogging about crisp bio-S&T, especially CRISPR.


[出典] "Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells" Wang Y, Wu J, Chen H, Yang Y, Xiao C, Yi X [..] Ge J, Zhou W, Chu X, Chen C, Zhou X, Wang L, Guan K, Qu L. Sci Adv 2021-01-27. ... もっと読む

[出典] "Exploring the Trans-Cleavage Activity of CRISPR-Cas12a for the Development of a Mxene Based Electrochemiluminescence Biosensor for the Detection of Siglec-5" Zhang K [..] Pan J. Biosens Bioelectron. 2021-01-26. ... もっと読む

[出典] "Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7" Wisnovsky S [..] Bertozzi CR. PNAS. 2021-01-25. 癌細胞はその表面を糖鎖で覆い、その糖鎖が免疫を ... もっと読む

[出典] "Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer" Bao M H-R, Yang C, Tse A P-W, Wei L [..] Wong C-M, Wong C C-L. Cell Rep 2021-01-26. ... もっと読む

2021-01-30 21:00 論文URL修正[出典] "Crispr editing of the gli1 first intron abrogates gli1 expression and differentially alters lineage commitment" Galat Y [..] Galat V, Iannaccone PM. Stem Cells 2021-01-26. https://stemcellsjournals.onlinelibrary.wiley.c ... もっと読む