[出典] "A CRISPR/CAS9‐based strategy targets the personalized chimeric neosequence in fusion‐driven cancer genome for precision medicine" Huang W, Zeng Z-C [..] Luo X-Q, Fang K. Clin Transl Med 2021-03-17. https://doi.org/10.1002/ctm2.355 中山大学の研 …
続きを読む
2021年03月
[レビュー] 腫瘍療法の次のフロンティア: ゲノム工学を介して腫瘍溶解性バクテリアの臨床応用を目指す
[出典] REVIEW "The next frontier of oncotherapy: accomplishing clinical translation of oncolytic bacteria through genetic engineering" Dailey KM et al. Future Microbiol. 2021-03-23. https://doi.org/10.2217/fmb-2020-0245 North Dakota State Universityを …
続きを読む
CRISPR/Cas9/rAAV6をベースとするRAG2欠損の遺伝子治療
[出典]"Gene Editing Rescues In vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System" Gardner C, Pavel-Dinu M [..] Acuto O, Porteus MH, Notarangelo LD. J Clin Immunol. 2021-03-01. https://doi.org …
続きを読む
メチル化PKP2がβ-カテニン安定化を介して肺癌の放射線抵抗性をドライブする
[出典] "CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin" Cheng C [..] Sang Y. Oncogene. 2021-03-19. https://doi.org/10.1038/s41388-021-01692-x 南昌大学第三附属医院を主 …
続きを読む
CRISPR/Casをベースとして髄膜腫におけるNF2欠損をモデリング
[リンクのみ] "Crispr/Cas-based modeling of NF2 loss in meningioma cells" Waldt N [..] Mawrin C. J Neurosci Methods. 2021-03-19. https://doi.org/10.1016/j.jneumeth.2021.109141 …
続きを読む