[出典] "High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination" Yuen CTL [..] Wong ASL. Nucleic Acids Res. 2022-01-21. https://doi.org/10.1093/nar/gkab1291 香港大学にKarolinska Institutetなどが加わっ ...
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2022年01月
CRISPRaにより,ヒト多能性幹細胞への高忠実度な初期化を実現
[出典] "CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells" Sakka J, Yoshihara M, Kvist J [..] Trokovic R. Stem Cell Reports. 2022-01-04. https://doi.org/10.1016/j.stemcr.2021.12.017 University of HelsinkiにKarolinska ...
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[レビュー] In vitroでのRNA検出に最適なCRISPR-Casシステムを選択する法
[出典] REVIEW "How to Find the Right RNA-Sensing CRISPR-Cas System for an In Vitro Application" Díaz-Galicia E, Grünberg R, Arold ST. Biosensors. 2022-01-19. https://doi.org/10.3390/bios12020053 King Abdullah University of Science and Technology (KAUST ...
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[レビュー] Cas12aをベースとした最新のウイルスDNA検出ツール設計に向けて
[出典] REVIEW "Towards application of CRISPR-Cas12a in the design of modern viral DNA detection tools" Dronina J, Samukaite-Bubniene U, Ramanavicius A. J Nanobiotechnol. 2022-01-21. https://doi.org/10.1186/s12951-022-01246-7 Center for Physical Sciences ...
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研究資源が限られた環境で利用可能な病原体検出システムをdCas9をベースとして開発
[出典] "CRISPR-dCas9 based DNA detection scheme for diagnostics in resource-limited settings" Bengtson M [..] Dekker C. Nanoscale. 2022-01-19. https://doi.org/10.1039/D1NR06557B Delft University of Technologyの研究グループは今回,dCas9をベースとして,ヒ ...
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