crisp_bio

RIKEN (NISLO, WDCM ...) - NIG (DDBJ/CIB, WDCM, OECD BRC, GBIF, JST BIRD, TPRP ...) - FREE

2022年02月

[出典] "Effect of Aphidicolin, a Reversible Inhibitor of Eukaryotic Nuclear DNA Replication, on the Production of Genetically Modified Porcine Embryos by CRISPR/Cas9" Navarro-Serna S [..] Gadea J. Int J Mol Sci. 2022-02-15. https://doi.org/10.3390/ijms2 ... もっと読む

[出典] "Considerations and practical implications of performing a phenotypic CRISPR/Cas survival screen" Ashoti A, Simone F [..] Eagan K, Gijsen N. PLoS One. 2022-02-17. https://doi.org/10.1371/journal.pone.0263262　Hubrecht Institute (Utrecht)，Broad Ins ... もっと読む

[注] 血友病A (HA)は単一遺伝子 (F8)欠損により発症するが，血漿中の凝固第VIII因子 (FVIII)濃度のわずかな上昇で，る臨床症状を大幅に改善可能[出典] "Therapeutic correction of hemophilia A using 2D endothelial cells and multicellular 3D organoids derived from CRI ... もっと読む

[注] 1950年代からアミノ酸生産菌として知られることになったCorynebacterium glutamicumは，現在も多様な化合物の生産工場として期待され開発が続けられている[出典] "CRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an L-proline exporter for L- ... もっと読む

[出典] "CRISPR-Detector: Fast and Accurate Detection, Visualization, and Annotation of Genome Wide Mutations Induced by Gene Editing Events" Huang L, Wang D [..] Chen T, Jiang Y. bioRxiv. 2022-02-19 [プレプリント]. https://doi.org/10.1101/2022.02.16.4807 ... もっと読む

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