[出典] PROTOCOL "A Method to Reduce off-Targets in CRISPR/Cas9 System in Plants" Movahedi A et al. In: Mysore K.S., Senthil-Kumar M. (eds) Plant Gene Silencing. MIMB 2022-03-25. https://doi.org/10.1007/978-1-0716-1875-2_21 南京林業大学を主とする研究グル …
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2022年04月
農業害虫Lygus hesperusの目の色素遺伝子編集: RNAiによるノックダウンとCRISPR/Cas9ノックアウト
[出典] "CRISPR-mediated knockout of cardinal and cinnabar eye pigmentation genes in the western tarnished plant bug"Heu CC [..] Fabric JA. Sci Rep 2022-03-22. https://doi.org/10.1038/s41598-022-08908-4 Arid Land Agricultural Research Center (USDA ARS)の …
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mRNA医薬開発に資するmRNAの構造,安定性,および翻訳の最適化
[出典] "Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics" Leppek K, Byeron GW, Kladwang W, Wayment-Steele HK [..] Das R. (bioRxiv 2021-03-30) Nat Commun. 2022-03-22. https://doi.org/10.1038/s41467-022-287 …
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SDA法にCRSPR-Cas14aを組み合わせた胆管がん関連血中循環マイクロRNAの迅速かつ等温的検出
[出典] "CRISPR-Cas14a-integrated strand displacement amplification for rapid and isothermal detection of cholangiocarcinoma associated circulating microRNAs" Chi X, W Y [..] Yang W, Huang J. Anal Chim Acta 2022-03-25. https://doi.org/10.1016/j.aca.2022.33 …
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非DNAバイオマーカーの超高感度検出を可能にするDNAウォーカー増幅型「一対多」Cas12aバイオセンサー
[出典] "An exceptional and universal DNA walker amplified “one-to-many” CRISPR/Cas12a-mediated fluorescent biosensor for ultrasensitive detection of non-DNA biomarkers" Li C-Y et al. Sens Actuators B Chem 2022-03-25. https://doi.org/10.1016/j.snb.2022.1 …
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