[出典] REVIEW "Dynamics and mechanisms of CRISPR-Cas9 through the lens of computational methods" Saha A, Arantes PR, Palermo G. Curr Opin Struct Biol 2022-06-08. https://doi.org/10.1016/j.sbi.2022.102400 [著者所属] University of California Riverside 著者 …
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2022年06月
Cas9/sgRNA RNPを接合体に注入することで,疾患モデルマウスを効率的かつ迅速に作製
[出典] "Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes" Sanchez-Baltasar R, Garcia-Torralba A [..] Navarro M, Segovia JC, García-Bravo M. M. CRISPR J 2022-06-08. https://doi.org/10.1089/cr …
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[レビュー] CRISPRゲノム編集による循環器系疾患のモデル構築と治療
[出典] REVIEW "CRISPR Modeling and Correction of Cardiovascular Disease" Liu N, Olson EN. Circ Res. 2020-06-20. https://doi.org/10.1161/CIRCRESAHA.122.320496 [著者所属] U Texas Southwestern Medical Center CRISPRゲノム編集の出現は,循環器研究の新時代を切 …
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CRISPR/Cas9による大型dsDNAウイルスの高効率なゲノム工学
[出典] "High-throughput engineering of cytoplasmic- and nuclear-replicating large dsDNA viruses by CRISPR/Cas9" López-Muñoz AD, Rastrojo A, Martín R, Alcamí A. bioRxiv 2022-06-13 [プレプリント]. https://doi.org/10.1101/2022.06.13.495503 [著者所属] Cen …
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CRISPR-AsCas12aにより, 眼白子症患者由来iPSCにおいて, 病因変異を効率的に修正
[出典] "CRISPR-AsCas12a Efficiently Corrects a GPR143 Intronic Mutation in Induced Pluripotent Stem Cells from an Ocular Albinism Patient" Torriano S et al. CRISPR J 2022-06-08. https://doi.org/10.1089/crispr.2021.0110 [著者所属] UCLA, UCLA School of Med …
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