[注] AML (急性骨髄性白血病)[出典] "Genome-wide CRISPR/Cas9 Screen Identifies Etoposide Response Modulators Associated with Outcomes in Pediatric AML" Nguyen NH [..] Lamba JK. Blood Adv 2022-09-16. https://doi.org/10.1182/bloodadvances.2022007934 [著者所属 ...
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2022年09月
CRISPR/dCas9-Dnmt3aによるAPPのDNAメチル化を介して、ADモデルマウスの脳病理をレスキュー
[注] Dnmt3a (DNAメチル化酵素)；APP (アミロイド前駆体タンパク)；AD (アルツハイマー病)[出典] "CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer’s disease" Park H [..] Kim J. Transl Neurodege ...
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CRISPR-Cas9をベースとする代謝工学により、Issatchenkia orientalisのセルロース加水分解性能を活用
[注] Issatchenkia orientalis (Candida krusei; Pichia kudriavzevii ) [*][出典] "Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates" Lee YG, Jin YS. J Agric Food Chem 2022-09-14. https://d ...
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ヘモグロビンE/βサラセミア症不死化細胞において、CRISPR/Cas9システムによりヘモグロビンEの変異を修正
[出典] "Genetic correction of haemoglobin E in an immortalised haemoglobin E/beta‐thalassaemia cell line using the CRISPR/Cas9 system" Trakarnsanga K [..] Wattanapanitch M. Sci Rep 2022-09-16. https://www.nature.com/articles/s41598-022-19934-7 https://do ...
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シロイヌナズナにおけるCRISPR/Cas9誘導・相同組み換え修復過程を介した遺伝子ターゲッティングの検証
[出典] "Insights into the molecular mechanisms of CRISPR/Cas9-mediated gene targeting at multiple loci in Arabidopsis" Zhang Z [..] Zhu JK, Miki D. Plant Physiol 2022-09-15. https://doi.org/10.1093/plphys/kiac431 [著者所属] Shanghai Center for Plant Stre ...
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