[出典] "Single gene mutation in a plant MYB transcription factor causes a major shift in pollinator preference" Lüthi MN, Berardi AE, Mandel T, Freitas LB, Kuhlemeier C. Current Biol 2022-12-05/12-19. https://doi.org/10.1016/j.cub.2022.11.006 [著者所属 …
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2022年12月
ヒストンメチル化阻害剤3DZNepが, CRISPR-Cas9ゲノム編集時のHDR経路の選択を促進する
[出典] "The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing" Bischoff N [..] Brakebusch C. Gene Genome Ed. 2022-12-18. https://doi.org/10.1016/j.ggedit.2022.100023 [著者所属] U Copenhagen, AstraZeneca, Max Delbr …
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CRISPR/Cas9-RAD51プラスミドの導入によるKOとKIの効率向上
[出典] "Elevated expression of exogenous RAD51 enhances the CRISPR/Cas9-mediated genome editing efficiency" Park SJ, Yoon SB, Choi EH, Hyeon H, Lee K, Kim KP. BMB Reports 2022-12-14. https://pubmed.ncbi.nlm.nih.gov/36513383/ [著者所属] Chung-Ang U (Seoul) …
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CRISPRiを利用して、併用療法に有効な新規薬剤候補を同定する
[出典] "An efficient CRISPR interference-based prediction method for synergistic/additive effects of novel combinations of anti-tuberculosis drugs" Samukawa N, Yamaguchi T, Ozeki Y et al. Microbiology 2022-12-19. https://doi.org/10.1099/mic.0.001285 [著者 …
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[レビュー] 増幅不要なCRISPRDx: 課題, 戦略, そして展望
[出典] REVIEW "Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives" Li H [..] Yin K. Chem Soc Rev 2022-12-19. https://doi.org/10.1039/d2cs00594h [著者所属] Shanghai Jiao Tong U School of Medicine, One Health Center …
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