[注] OMEGA (Obligate Mobile-Element Guided Activity)[出典] Review "Recent application of CRISPR-Cas12 and OMEGA system for genome editing" Badon IW, Oh Y, Kim H-J, Lee SH. Mol Ther. 2023-11-10. https://doi.org/10.1016/j.ymthe.2023.11.013 [著者所属] 中央大 …
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2023年11月
自閉症スペクトラム障害 ・不安モデルマウスのゲノムの一部重複を除去するとシナプス伝達と行動が回復する
[出典] "Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer" Bustos FJ, Pandian S, Haensgen H et al. BMC Biol 2023-11-14. https://doi.org/10.1186/s12915-023-01714-y [著者所属] MIT, U An …
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DNA記憶素子: ゲノム配列暗号化をマルチサイト塩基編集を利用して生細胞内で実現
[出典] "Cryptography in the DNA of living cells enabled by multi-site base editing" Volf V [..] Chen F, Church GM. bioRxiv 2023-11-15 [Preprint] https://doi.org/10.1101/2023.11.15.567131 [著者所属] Harvard Medical School, Harvard U, Wyss Institute for Bio …
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線虫の精子形成研究のためのCRISPR-Cas9ゲノム編集プロトコル
[出典] "Protocol for CRISPR-Cas9-mediated genome editing to study spermatogenesis in Caenorhabditis elegans " Wang P, Cao Z, Wang Q [..] Zhao Y, Miao L. STAR Protoc 2023-11-14. https://doi.org/10.1016/j.xpro.2023.102720 [著者所属] 生物物理研究所 (北京) …
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ヒト極性気道上皮への組換えAAV (rAAV2.5T) 導入における宿主必須因子の同定
[出典] "Identification of host essential factors for recombinant AAV transduction of the polarized human airway epithelium" Has S [..] Liu J. J Virol 2023-11-15. https://doi.org/10.1128/jvi.01330-23 [著者所属] U Kansas Medical Center, U Iowa, GeneGoCell …
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