[出典] "Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer" Furusawa T [..] Weyemi U. Mol Carcinog. 2024-02-27. https://doi.org/10.1002/mc.23705 [所属] NCI/NIH, U Tex …
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2024年03月
CRISPR-Cas9によるdsRNaseをノックアウトを介してツマジロクサヨトウに対するRNAiの効果を向上
[出典] "CRISPR-Cas9 mediated dsRNase knockout improves RNAi efficiency in the fall armyworm" Koo J, Zhu GH, Palli SR. Pestic Biochem Physiol. 2024-02-23. https://doi.org/10.1016/j.pestbp.2024.105839 [所属] U Kentucky. 翅目昆虫はRNA干渉(RNAi)反応、特 …
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Cas9/デュアルsgRNAを介したBCR-ABL融合遺伝子の破壊によって、慢性骨髄性白血病細胞の増殖を阻害し、アポトーシスを誘導
[出典] "Targeted disruption of the BCR-ABL fusion gene by Cas9/dual-sgRNA inhibits proliferation and induces apoptosis in chronic myeloid leukemia cells" Zeng J, Liang X, Duan L, Tan F [..] Luo D, Hu Z. Acta Biochim Biophys Sin (Shanghai). 2024-02-28. h …
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CRISPR/Cas9を用いたクロトー遺伝子の過剰発現は、ヒト大腸癌細胞においてアポトーシスを誘導し細胞運動を抑制する
[出典] "Overexpression of Klotho gene using CRISPR/Cas9 induces apoptosis and inhibits cell motility in the human colorectal cancer cells" Soykan MN, Gunes S. Biotechnol J. 2024-02-25. https://doi.org/10.1002/biot.202300496 [所属] Eskisehir Osmangazi U (T …
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効率的な遺伝子編集と腫瘍増感治療のための生物学的産生とMOF導入デュアルカットCRISPR/Cas9システム
[注] MOF (Metal Organic Frameworks / 金属有機構造体)[出典] "Biologically produced and metal-organic framework delivered dual-cut CRISPR/Cas9 system for efficient gene editing and sensitized cancer therapy" Yu J, Tang M [..] Li Y, Tian L. Acta Biomater. 20 …
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