2020-08-19 8月19日の新規公開3エントリーならびに関連する公開済エントリーを追加
[crisp_bio注]
- ブログ投稿1件ごとの字数制限のため, SRAS-CoV-2の構造のPDB登録エントリーを順次分割して投稿: その５(本記事);- その４; - その３; - その２; - その１
7月22日 (本投稿)から、同一論文・投稿 (to be publishedを含む)ごとの形式を採用、このため、新規公開エントリーより以前に公開されたエントリーも改めてリストしている。
- To be publishedの場合, そのTitleは仮置の場合もあり、ジャーナルからの公開時には変更されている可能性がある。
- カラムRelease Dateの"AUTH"は"編集処理済、登録者の確認・同意待ち"を意味する
- 出典: PDBj 新型コロナウイルスの構造情報2020-08-05までの更新履歴
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ID |
Title |
Release Date |
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投稿 |
X-ray Structure of SARS-CoV-2 main protease bound to … |
to be published |
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X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A |
08/19/2020 |
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X-ray Structure of SARS-CoV-2 main protease bound to Boceprevir at 1.45 A |
05/06/2020 |
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Structure of COVID-19 main protease bound to potent broad-spectrum non-covalent inhibitor X77 |
03/25/2020 |
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投稿 |
Crystal structure of the SARS-CoV-2 main protease in complex with … |
to be published |
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Crystal structure of the SARS-CoV-2 main protease in complex with Boceprevir (space group P212121) |
08/19/2020 |
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7C7P |
Crystal structure of the SARS-CoV-2 main protease in complex with Telaprevir |
07/29/2020 |
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投稿 |
Closing coronavirus spike glycoproteins by structure-guided design. |
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Prefusion SARS-CoV-2 S ectodomain trimer covalently stabilized in the closed conformation |
08/19/2020 |
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投稿 |
Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains |
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Structure of SARS-CoV-2 spike at pH 4.0 |
08/12/2020 |
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Consensus structure of SARS-CoV-2 spike at pH 5.5 |
08/12/2020 |
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Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 1 |
08/12/2020 |
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Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 2 |
08/12/2020 |
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投稿 |
Crystal structure of SARS CoV2 main protease in complex with inhibitor … |
to be published |
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Crystal structure of SARS CoV2 main protease in complex with inhibitor Boceprevir |
08/12/2020 |
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Crystal structure of SARS CoV2 main protease in complex with inhibitor Telaprevir |
08/12/2020 |
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投稿 |
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. |
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apo SARS-CoV-2 S trimer |
AUTH |
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SARS-CoV-2 S trimer in complex with one Fab |
AUTH |
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SARS-CoV-2 S trimer in complex with two Fabs |
AUTH |
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SARS-CoV-2 S trimer in complex with three Fabs |
AUTH |
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The interface of H014 Fab binds to SARS-CoV-2 S |
08/12/2020 |
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投稿 |
The crystal structure of papain-like protease of SARS CoV-2, …….. |
to be published |
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The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441 |
08/12/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2 , P3221 space group [The crystal structure of Papain-Like Protease of SARS CoV-2 , P3221 space group] |
05/27/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant |
05/06/2020 |
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The crystal structure of papain-like protease of SARS CoV-2 |
05/06/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, P3221 space group |
05/27/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder530 |
08/05/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant |
05/06/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, at room temperature |
06/24/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder457 |
08/05/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder495 |
08/05/2020 |
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The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder530 |
08/05/2020 |
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投稿 |
Identification of a putative peptide-binding site at the dimer interface of the SARS-CoV-2 Nsp9 RNA-replicase. |
to be published |
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SARS-CoV-2 Nsp9 RNA-replicase |
05/20/2020 |
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Peptide-bound SARS-CoV-2 Nsp9 RNA-replicase |
08/05/2020 |
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Peptide-bound SARS-CoV-2 Nsp9 RNA-replicase |
04/08/2020 |
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投稿 |
H11-H4 bound to Spike |
to be published |
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H11-H4 bound to Spike |
07/29/2020 |
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投稿 |
Crystal structure of the SARS-CoV-2 helicase at 1.94 Angstrom resolution |
to be published |
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Crystal structure of the SARS-CoV-2 helicase at 1.94 Angstrom resolution |
07/29/2020 |
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投稿 |
H11-D4 complex with SARS-CoV-2 RBD |
to be published |
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H11-H4 complex with SARS-CoV-2 |
07/29/2020 |
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投稿 |
Structure of SARS-CoV-2 RdRp/RNA complex at 3.4 Angstroms resolution |
to be published |
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SARS-CoV-2 RdRp/RNA complex |
07/29/2020 |
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投稿 |
Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures |
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SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP OPEN CONFORMATION) |
07/29/2020 |
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SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation) |
07/29/2020 |
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SARS-CoV-2 spike in prefusion state |
07/29/2020 |
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投稿 |
SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation |
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SARS-CoV-2-Nsp1-40S complex, composite map |
07/22/2020 |
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SARS-CoV-2-Nsp1-40S complex, focused on head |
07/22/2020 |
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SARS-CoV-2-Nsp1-40S complex, focused on body |
07/29/2020 |
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投稿 |
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 |
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SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 |
07/29/2020 |
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SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 |
07/29/2020 |
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SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 |
07/29/2020 |
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SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex |
07/29/2020 |
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SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit |
07/29/2020 |
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投稿 |
A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike |
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Structure of SARS-CoV-2 spike at pH 5.5, all RBDs down |
07/29/2020 |
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投稿 |
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex. |
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Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC |
07/29/2020 |
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投稿 |
Extreme malleability of the SARS-CoV-2 3CL Mpro active site cavity facilitates binding of clinical antivirals: Prospects for repurposing existing drugs and ramifications for inhibitor design |
To be published |
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3C-like proteinase, (1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropyla mino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide |
07/22/2020 |
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3C-like proteinase, (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide |
07/22/2020 |
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3C-like proteinase, boceprevir (bound form) |
07/22/2020 |
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投稿 |
SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation |
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SARS-CoV-2-Nsp1-40S complex, composite map |
07/22/2020 |
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SARS-CoV-2-Nsp1-40S complex, focused on head |
07/22/2020 |
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SARS-CoV-2-Nsp1-40S complex, focused on body |
07/29/2020 |
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投稿 |
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Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site) |
07/22/2020 |
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Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State |
07/22/2020 |
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Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State |
07/22/2020 |
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Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State |
07/22/2020 |
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Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State |
07/22/2020 |
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Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State |
07/22/2020 |
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投稿 |
Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike |
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Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4 |
07/22/2020 |
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投稿 |
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Distinct conformational states of SARS-CoV-2 spike protein |
07/22/2020 |
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Distinct conformational states of SARS-CoV-2 spike protein |
07/22/2020 |
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投稿 |
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant |
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SARS-CoV-2 Spike D614G variant, minus RBD |
07/22/2020 |
更新履歴
2020-08-12 8月22日公開8エントリーを追加
2020-08-05 8月5日公開エントリーを追加
2020-07-29 7月29日公開エントリーを追加: 15 エントリ / 9 投稿 (論文, プレプリントまたはto be publsihed)
2020-07-24 7-22エントリー追加分のうち#1のPDB IDの誤記を修正: 6XRBを6XS6に修正
2020-07-22 エントリー14件追加 (#51 から#36まで);
2020-07-15 PDB 2020-07-15 公開エントリー２件を追加
2020-07-08 PDB 2020-07-08 公開エントリーを追加
#27と#28は2020-06-24公開であるが#29と同じbioRxiv 2020-06-13投稿掲載構造ということで再掲。
2020-07-01 PDB 2020-07-01 公開エントリーを追加
07-01公開エントリーについては、同一投稿または論文掲載分を1行にまとめた
(その中に07-01より以前に公開されたエントリーも再掲)
2020-06-28 PDB2020-06-24公開11エントリーを収録
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