[出典] REVIEW "The role of long noncoding RNAs in ocular angiogenesis and vascular oculopathy" Gandhi P, Wang Y, Li G, Wang S. Cell Biosci. 2024-03-23. https://doi.org/10.1186/s13578-024-01217-5 [所属] Tulane U School of Medicine, Louisiana State U School of Medicine, Tongji Medical College (Huazhong U Science and Technology), Tulane U.

Introduction

Ocular angiogenesis, vascular oculopathies and current treatments

Table 1 Vascular Oculopathies and Current Treatments

LncRNAs and their functional mechanisms

Fig. 1 Nuclear Mechanisms of lncRNAs

Fig. 2 Cytoplasmic mechanisms of LncRNAs

LncRNAs in angiogenesis and vascular diseases

Literature search of lncRNAs involved in vascular oculopathies

Regulation of LncRNAs in vascular oculopathies

Functional study of lncRNAs in ocular angiogenesis

Table 2 Pro-angiogenic lncRNAs

Fig. 3 ~ Fig. 13 ANRIL ~ PNKY

In vitro studies of lncRNAs

Human/primate specific LncRNAs in ocular angiogenesis

Fig. 14 LncEGFL7OS

Conclusion remarks, future directions