イネの粒の大きさは、収量と品質の双方に影響することから、イネの遺伝子改良の重要なターゲットとなっている。この総説では、中国の研究チームが、既知の粒径関連遺伝子と粒径改変のためのCRISPR/Cas9の利用について要約し、イネの粒径改良へのCRISPR/Cas9の応用の可能性について議論している。
[出典] "Genetic Improvement of rice Grain size Using the CRISPR/Cas9 System" Zhang T, Wang Z, Liu Q, Zhao D. Rice. 2025-01-27. https://doi.org/10.1186/s12284-025-00758-8 [所属] Key Laboratory of Plant Functional Genomics of the Ministry of Education / Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding (Yangzhou U)
[構成]
Introduction
CRISPR/Cas9 System
Major Classification of gene Editing Tools
Functions of Various CRISPR/Cas9 Systems
Available gene Resources for Grain size Improvement
Nucleotide Variations in Genes with Positive Effects
Nucleotide Variations in Genes with Negative Effects
Nucleotide Variations in Genes with Opposite Effects on Grain Length and Width
Utilizing CRISPR/Cas9 to Rationally Design Grain size
Demand for Grain size Improvement
Editing Strategy for Improving Grain size
Gene Regulatory Effect
Multiple gene Editing
Conclusion and Perspectives
Grain size Genes and Their Interactions
CRISPR/Cas9 for Rapid Improvement
Optimizing CRISPR/Cas9 to Improve Grain size
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