[出典] "Generation of murine tumor models refractory to αPD-1/-L1 therapies due to defects in antigen processing/presentation or IFNγ signaling using CRISPR/Cas9" Chariou PL [..] Schlom J, Gameiro SR. PLoS One 2024-03-01. https://doi.org/10.1371/journal ...
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タグ:がん
CRISPR/Cas9スクリーンにより、前立腺癌転移の新規必須遺伝子を同定
[出典] "CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel essential gene in prostate cancer metastasis" Rodrigo-Faus M [..] Gutierrez-Uzquiza A. Cancer Lett. 2024-03-01. https://doi.org/10.1016/j.canlet.2024.216776 [所属] Comp ...
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バイオミメティック細菌由来ナノクラスターがCRISPR遺伝子編集と光熱性調節の相乗効果によりフェロトーシス癌免疫療法を強化する
[出典] "Biomimetic bacteria-derived nanoclusters enhance ferroptosis cancer immunotherapy through synergistic CRISPR-photothermo modulation" Pan X [..] Shen Q. Nano Today 2024-02-29. https://doi.org/10.1016/j.nantod.2024.102213 [所属] Shanghai Jiao Tong U ...
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[レビュー] 癌免疫療法を強化するGMPに基づいたCRISPR/Cas9技術
[注] GMP (Good Manufacturing Practice / 医薬品の製造管理及び品質管理の基準)[出典] Review "GMP-manufactured CRISPR/Cas9 technology as an advantageous tool to support cancer immunotherapy" Caforio M, Iacovelli S, Quintarelli C, Locatelli F, Folgiero V. J Ex ...
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Cas9/デュアルsgRNAを介したBCR-ABL融合遺伝子の破壊によって、慢性骨髄性白血病細胞の増殖を阻害し、アポトーシスを誘導
[出典] "Targeted disruption of the BCR-ABL fusion gene by Cas9/dual-sgRNA inhibits proliferation and induces apoptosis in chronic myeloid leukemia cells" Zeng J, Liang X, Duan L, Tan F [..] Luo D, Hu Z. Acta Biochim Biophys Sin (Shanghai). 2024-02-28. h ...
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