crisp_bio

RIKEN (NISLO, WDCM ...) - NIG (DDBJ/CIB, WDCM, OECD BRC, GBIF, JST BIRD, TPRP ...) - FREE

タグ:オルガノイド

[注] 胃がん (Gastric Cancer: GC);患者由来オルガノイド (patient-derived organoids: PDOs);KDM1A (ヒストンリジンデメチラーゼ-1A)[出典] "CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability" M ... もっと読む

[出典] "Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis" Hendriks D [..] Artegiani B, Clevers H. Nat Biotechnol 2023-02-23. https://doi.org/10.1038/s41587-023-01680-4 [著者所属] Hubrecht Institut ... もっと読む

[出典] "CRISPR-Cas9-Mediated Correction of SLC12A3 Gene Mutation Rescues the Gitelman’s Disease Phenotype in a Patient-Derived Kidney Organoid System" Lim SW [..] Yang CW. Int J Mol Sci 2023-02-03. https://doi.org/10.3390/ijms24033019 [著者所属]  Catho ... もっと読む

[注] アセンブロイド (Assembloid):異なる脳部位から構成される脳オルガノイド[出典] "CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development" Meng X [..] Pașca SP. bioRxiv 2022-09-06 [プレプリント]. https://doi.or ... もっと読む

[NEWS RELEASE] "Mode-of-action of T-cell immunotherapies in focus" Princess Máxima Center for Pediatric Oncology. EurekAlert! 2022-07-25. https://www.eurekalert.org/news-releases/959714[YouTubeビデオ] [論文] "Uncovering the mode of action of engineered T ... もっと読む

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