blogging about crisp bio-S&T, especially CRISPR.


2020-05-16 Cell論文出版2019-10-23 初稿[出典] An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cell. Bowling S, Sritharan D [..] Hormoz S, Camargo FD. bioRxiv. 2019-10-17 > Cell 2020 ... もっと読む

[出典] "Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments" Benhalevy D, Anastasakis DG, Hafner M. Nat Methods. 2018-11-26.RNAの細胞内小器官局在を解析する手法として、APEX-RIP (RNA immunoprecipitation)やRaPIDな ... もっと読む

(構造生命科学ニュースウオッチ2016/03/30から転載)[出典] [技術プレビュー] Yihan Lin & Michael B. Elowitz "Central Dogma Goes Digital" Mol.Cell 2016 Mar 17;61(6):791-792. [技術報告] Cem Albayrak et al. "Digital Quantification of Proteins and mR ... もっと読む

(構造生命科学ニュースウオッチ2016/03/22から転載)[出典]Edroaldo Lummertz da Rocha et al. "NetDecoder: a network biology platform that decodes context-specific biological networks and gene activities.." Nucleic Acids Res. Published online 2016 ... もっと読む

[出典] "A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles" Subramanian A, ~ Golub TR. Cell. 2017 Nov 30;171(6):1437–1452.e17. (bioRxiv. Posted May 10, 2017. )Broad Instituteを中心とする研究チームは2006年に、遺伝子発現の ... もっと読む