blogging about crisp bio-S&T, especially CRISPR.


[PERSPECTIVE] Molecular messages in human microbiota. Henke MT, Clardy J. Science. 2019-12-13. Harvard Medical School 生物化学・分子薬理学部のJ. Clardyらが、Science Perspectiveにて、対照的な手法によりマイクロバイオームに由来する低分子の機能解析を実現し ... もっと読む

[出典] Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes. Sberro H [..] Bhatt AS. Cell. 2019 Aug 22;178(5):1245-1259.e14. Online 2019 Aug 8. (bioRxiv 2018-12-13); PREVIEW Tiny Hidden Genes within Our Microbiome. Mittelman K, ... もっと読む

[出典] Targeted isolation and cultivation of uncultivated bacteria by reverse genomics. Cross KL, Campbell JH [..] Podar M. Nat Biotechnol. 2019-09-30.背景長年にわたりヒトをはじめとする生物から土壌をはじめとする環境までに、膨大な種類の微生物が生息するとさ ... もっと読む

[出典] "CRISPR-Cas System of a Prevalent Human Gut Bacterium Reveals Hyper-targeting against Phages in a Human Virome Catalog" Soto-Perez P, Bisanz JE, Berry JD, Lam KN, Bondy-Denomy J, Turnbaugh PJ. Cell Host & Microbe. 2019-09-03 UCSFの研究グループは ... もっと読む

[出典] "Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes" Riquelme E, Zhang Y [..] McAllister F. Cell 2019-08-08;"Bacteria on tumors influences immune response and survival of patients with pancreatic cancer"MD Anderson Can ... もっと読む