blogging about crisp bio-S&T, especially CRISPR.


[出典] PROTOCOL "Production of Human CRISPR-Engineered CAR-T Cells" Agarwal S, Wellhausen N, Levine BL, June CH. J Vis Exp. 2021-03-15.  University of PennsylvaniaのCAR-T療法開発 [*]研究チームがCAR-T細胞の構築法を解説: CRIS ... もっと読む

[出典] REVIEW "Interrogating immune cells and cancer with CRISPR-Cas9" Buquicchio FA, Satpathy AT. Trends Immunol. 2021-03-31. Stanford University School of Medicineの著者らが,CRISPR-Cas9技術の最新動向を概観し, ... もっと読む

[出典] PREVIEW "Erasing iatrogenic neoantigens from in vivo CRISPR screens" Yi F, Klebanoff CA. Immunity. 2021-03-09.; [論文] "In vivo screens using a selective CRISPR antigen removal lentiviral vector system ... もっと読む

[出典] "Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing" Mattsson J [..] Nilsson B. Nat Commun. 2021-02-24. 抗体医薬 (therapeutic antibody)が悪性腫 ... もっと読む

[PREVIEW] How to make a better T cell: in vivo CRISPR screens have some answers. Villa M, Stanczak MA, Pearce EL. Cell 2021-03-04. Cell誌から2021年2月25日にオンライン出版された2論文 [*]をハイライトし、それぞれの ... もっと読む