crisp_bio

blogging about crisp bio-S&T, especially CRISPR.

タグ:免疫・療法

[出典] REVIEW "CRISPR Takes the Front Seat in CART-Cell Development" Manriquez-Roman C, Siegler EL, Kenderian SS. BioDrugs 2021-02-27. https://doi.org/10.1007/s40259-021-00473-y Mayo Clinicの研究チームが、CRISPR技術により進行中の「自家T細胞をベースとする ... もっと読む

[出典] "Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor immunotherapy" Mo F [..] Hammock BD, Lu X. Sig Transduct Target Ther 2021-02-25. https://doi.org/10.1038/s41392-021-00462-1 広西医科大学とUC Davis ... もっと読む

[出典] "Efficient Immune Cell Genome Engineering with Enhanced CRISPR Editing Tools" Chan W [..] Germain RN. ImmunoHorizon 2021-02-01. https://doi.org/10.4049/immunohorizons.2000082 NIADI/NIHにJHUが加わった研究グループの成果。CRISPR-Casシステムをベースと ... もっと読む

[出典] "In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer" Chen Z [..] Wherry EJ, Shi J. Cell. 2021-02-25. https://doi.org/10.1016/j.cell.2021.02.019Graphical Abstract参照 https://ars.els-cdn.com/content/image/1-s2.0-S00 ... もっと読む

[出典] "In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions" Huang H, Zhou P [..] Chi H. Cell 2021-02-25. https://doi.org/10.1016/j.cell.2021.02.021 St. Jude Children’s Research Hospitalの研究グループは ... もっと読む

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