[注] LBP (Live Biotherapeutic Products; 生きた腸内細菌で構成される製剤)[出典] "Developing the Limosilactobacillus reuteri Chassis through an Endogenous Programmable Endonuclease-Based Genome Editing Tool" Guo Q [..] Zhao S, Peng N. ACS Synth Biol 2023-11- ...
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タグ:合成生物学
ゲノムを書き換える:ヒト疾患を忠実に再現するマウスモデルを作出可能にするゲノム工学
[出典]Research Briefing "Genome rewriting generates mouse models of human diseases" Ordoñez R, Zhang W. Nature 2023-11-01. https://doi.org/10.1038/d41586-023-03079-2 [著者所属] NYU Langone Health論文 "Mouse genome rewriting and tailoring of three importa ...
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CRISPR-Cas9が誘導するNHEJ過程を利用して、好塩菌H. bluephagenesis における大規模 (~50 kb) なDNA削除を実現
[出典] "CRISPR-Cas9 assisted non-homologous end joining genome editing system of Halomonas bluephagenesis for large DNA fragment deletion" Liu C, Yue Y, Xue Y, Zhou C, Ma Y. Microb Cell Fact 2023-10-14. https://doi.org/10.1186/s12934-023-02214-y [著者所属 ...
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高温エタノール生産菌Zymomonas mobilis のCRISPRをベースとする迅速かつ高効率なゲノム工学ツールを開発
[出典] "Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis " Zheng Y, Fu H [..] Liu Y, Yang J, Peng W. Microb Cell Fact 2023-10-13. https://doi.org/10.1186/s12934-023-02217-9 [著者所属] ...
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Cas9による大腸菌ゲノム工学に向けたAcrIIC1抗CRISPRタンパク質の特性解析
[出典] "Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli " Trasanidou D, Potocnik A, Barendse P [..] Staals RHJ, Mougiakos I. Commun Biol. 2023-10-13. https://doi.org/10.1038/s42003-023-05418-5 [著者所属] ...
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