crisp_bio

blogging about crisp bio-S&T, especially CRISPR.

タグ:塩基エディター

[出典] PROTOCOL "Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors" See JE, Shin HR, Jang G, Kweon J, Kim Y. J Vis Exp. 2021-02-28. https://doi.org/10.3791/61557 University of Ulsan College of Medicine (ソウル)の研究チームが先行 ... もっと読む

[出典] "Antisense RNA Interference-Enhanced CRISPR/Cas9 Base Editing Method for Improving Base Editing Efficiency in Streptomyces lividans 66" Zhang Y, Yun K, Huang H, Tu R, Hua E, Wang M. ACS Synth Biol. 2021-03-15. https://doi.org/10.1021/acssynbio.0c0 ... もっと読む

[出典] "PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants" Siegner S [..] Corn JE. BMC Bioinformatics 2021-03-02. https://doi.org/10.1186/s12859-021-04034-6; Webサイト http://fgcz-shiny.uzh.ch/PnBDesigner/  ... もっと読む

[出典] "Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins" Chen L [..] Chew WL. Nat Commun 2021-03-02. https://doi.org/10.1038/s41467-021-21559-9 Genome Institute of Singapore (A*STAR)の研究グループが今回、Cas ... もっと読む

[出典] "Engineered Prime Editors with PAM flexibility" Kweon J [..] Kim Y. Mol Ther 2021-02-23. https://doi.org/10.1016/j.ymthe.2021.02.022 University of Ulsan College of Medicineを主とする研究グループの成果。PE [*]は、塩基の置換, 挿入, および欠失をDSBや ... もっと読む

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