[出典] "Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4" Li X, Liao F [..] Li Z, Yu G, Yin H. Nucleic Acids Res 2023-08-17. https://doi.org/10.1093/nar/gkad669 [著者所属] Tianjin Medical U, Hubei U, Institute of Basic Medicine and Cancer CAS. [注] 2018年 ...
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タグ:抗CRISPR
[解説] Cas9を(R-)ループから遠ざける抗CRISPR (Acr) タンパク質
[出典] "Keeping Cas9 out of the (R-)loop" Swarts DC. PNAS 2023-08-22. https://doi.org/10.1073/pnas.2311727120 [著者所属] Wageningen U; Fig. 1 Simplified model of HpaCas9-mediated target DNA cleavage and inhibition by AcrIIC4. Acrタンパク質を研究すること ...
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AcrIIC4がR-ループ形成の阻害を介してタイプII-C CRISPR-Cas9を無力にする構造基盤
[出典] "AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation" Sun W, Cheng Z, Wang J [..] Wang Y. PNAS 2023-07-26. https://doi.org/10.1073/pnas.2303675120 [著者所属] Key Laboratory of RNA Biology (Institute of Biophysics CAS), National Laborator ...
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その構造比較から抗-CRSIPRタンパク質 (Acr)s の起源を探った
[出典] "Search for Origins of Anti-CRISPR Proteins by Structure Comparison" Sahakyan H, Makarova KS, Kooning EV. CRISPR J. 2023-06-01. https://doi.org/10.1089/crispr.2023.0011 [著者所属] NCBI バクテリアとアーケアに感染する多くのウイルスが、特定のCRSIPR- ...
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CRSIRPimmunity: CRISPR-Casシステムと抗CRISPRシステムの同定・検索を可能にするWebサーバー
[出典] "CRISPRimmunity: an interactive web server for CRISPR-associated Important Molecular events and Modulators Used in geNome edIting Tool identifYing" Zhou F, Yu X, Gan R, Ren K [..] Huang Z, Zhang F. Nucleic Acids Res. 2023-05-22. https://doi.org/10. ...
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