[注] 高速原子間力顕微鏡（HS-AFM）[出典] "Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy" Puppulin L [..] Shibata M. ACS Nano. 2023-02-27. https://doi.org/10.1021/acsnano.2c1 ...
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タグ：構造解析
タイプI-C CRISPRカスケードにおけるR-ループ形成の構造的スナップショット
[出典] "Structural snapshots of R-loop formation by a type I-C CRISPR Cascade" O’Brien RE [..] Taylor DW. Mol Cell. 2023-02-16. https://doi.org/10.1016/j.molcel.2023.01.024 [著者所属] UT Austin[構造情報]EMD-27402/PDB 8DEX Type I-C Cascade Apo StructureE ...
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CRISPR-Casに新たな"手品"が加わった：Craspase (ヌクレアーゼとプロテアーゼの共演)
[出典][NEWS & VEIWS] "CRISPR–Cas has a new juggling act: interplay between nuclease and protease" Rish AD, Fu TM. Nat Struct Mol Biol. 2023-01-31. https://doi.org/10.1038/s41594-022-00917-1 [著者所属] Ohio State U[論文] "Structural insights into the regu ...
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タイプIII-E CRISPR-Casエフェクターのクライオ電顕構造とプロテアーゼ活性
[出典] "Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector" Huo Y, Zhao H, Dong Q, Jiang T. Nat Microbiol. 2023-01-26. https://doi.org/10.1038/s41564-022-01316-4 [著者所属] Institute of Biophysics (Beijing), U Chinese Academy of ...
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Thermobaculum terrenum由来タイプI-B CRISPR Cas7の構造解析
[出典] "Structural characterization of the type I-B CRISPR Cas7 from Thermobaculum terrenum " Seo PW, Gu DH [..] Kim JS. Biochim Biophys Acta Proteins Proteom. 2023-01-20. https://doi.org/10.1016/j.bbapap.2023.140900 [著者所属] Chonnam National U, Poha ...
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