crisp_bio

crisp_bioはCRISPRのオーラも念頭においた命名でしたが,2021年からは専ら,CRISPR技術の開発と応用ならびにSRAS-CoV-2/COVID-19に関する投稿になってしまいました.データベース,生物資源センター,マイクロバイオーム,タンパク質デザインを取り上げたいと思いつつ.

タグ:癌

[出典] REVIEW "Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment" Xu X, Liu C [..] Zhang H. Adv Drug Deliv Rev 2021-07-26. https://doi.org/10.1016/j.addr.2021.113891; Graphical Abstract https://ars.els-cdn.com/content/image/1-s2.0-S0169409 ... もっと読む

[出典] "CRISPR screening identifies CDK12 as a conservative vulnerability of prostate cancer" Lei H, Wang Z, Jiang D, Liu F [..] Huang H, Liu Q, Png H. Cell Death Dis. 2021-7-27. https://doi.org/10.1038/s41419-021-04027-6 CRISPRスクリーニングで同定したCD ... もっと読む

[出典] "EGFR activation limits the response of liver cancer to lenvatinib" Jin H, Shi Y, Lv Y, Yua S [..] Zhou W, Zhai B, Qin W, Bernards R. Nature. 2021-07-21. https://doi.org/10.1038/s41586-021-03741-7 肝細胞癌 (Hepatocellular carcinoma, HCC)は,最も一 ... もっと読む

[出典] "Precise editing of FGFR3-TACC3 fusion genes with CRISPR-Cas13a provides a personalized therapeutic strategy for the treatment of human glioblastoma" Wu Y, Jin W [..] Wang J, Kang C. Mol Ther. 2021-07-15. https://doi.org/10.1016/j.ymthe.2021.07.002 ... もっと読む

[出典] "Comparative use of CRISPR and RNAi to modulate integrin α3β1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic α3β1 functions are independent of global regulation of the transcriptome" Kenney J, Ndoye A, Lama ... もっと読む

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