[出典] "Is duchenne gene therapy a suitable treatment despite its immunogenic class effect?" Tang A, Yokota T. Expert Opinion on Drug Safety. 2024-12-25. https://doi.org/10.1080/14740338.2024.2447072 [所属] U Alberta. デュシェンヌ型筋ジストロフィー（DM …
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タグ：神経変性
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[出典] "Optimized prime editing of the Alzheimer’s disease-associated APOE4 mutation" Rottner AK, Lunding A [..] Sienski G. Stem Cell Reports. 2024-11-29. https://doi.org/ 10.1016/j.stemcr.2024.11.002 [所属] AstraZeneca (Genome Engineering (Sweden); Data …
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APOE-ε4と運動トレーニングが脳微小血管内皮細胞バリア機能と代謝に及ぼす影響
[出典] "Impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism" Weber CM [..] Clyne AM. eBioMedicine. 2024-12-07. https://doi.org/10.1016/j.ebiom.2024.105487 [所属] U Maryland. これまでに、アル …
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[20241117更新] 脊髄小脳失調症1型マウスおよびヒトiPSC由来ニューロンにおけるATXN1のCas9編集
2024-11-17 Molecular Therapy Nucleic Acids 誌掲載"COMMENTARY" 記事の書誌情報を以下に追記："CRISPR-Cas9-directed gene therapy for spinocerebellar ataxia type 1" Miclăuș M, Balmus G. Mol Ther Nucleic Acids. 2024-11-14. https://doi.org/10.1016/j.omtn.202 …
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アルツハイマー病（AD）の老化脳にみられる転移因子群の調節異常
[注] 転移因子（transposable element: TE）[出典] "Widespread transposable element dysregulation in human aging brains with Alzheimer's disease" Feng Y [..] Cheng F. Alzheimers Dement. 2024-10-02. https://doi.org/10.1002/alz.14164 [所属] Cleveland Clinic, …
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